In the case of the TLR3 (rs3775291) SNP, we found a trend toward a lower incidence of CMV infection among carriers of the T allele in the homozygous state (40.0% for TT versus 57.6% for CC/CT; P-value = 0.099), suggestive of a recessive protective effect. The gene discussed is TLR3; the disease is cytomegalovirus infection.