CD177 and adrenal cortex carcinoma: Among the different functional gene sets, we noticed that ACC showed the downregulation of the immune system including immune response-activating cell surface receptor signaling pathway, immune system process, lymphocyte-mediated immunity, positive regulation of T-cell-mediated immunity, and the production of molecular mediator of immune response (p < 0.001) (Figure 5D) with detailed and interacted DEPs listed as PPI network (Figure 5E).