The focuses of RA-related CVD research shifted in the order of clinical features (#1, # 3, # 5, # 10), mechanism exploration (#0, #6, #15), anti-tumor necrosis factor therapy (# 4, #8, #14), CVD risk factors (#11, #13) and antirheumatic drug safety (#7, #12). Here, TNF is linked to rheumatoid arthritis.