To identify whether the ten proteins could be used in diagnosing SLE and developing a disease diagnosis model, we carried out univariate logistic regression analysis, and TNF RII, BLC, TNF RI, MIP-1b, eotaxin, MIG, IL-8, and MCP-1 showed statistical significance in distinguishing SLE patients from healthy controls (Table 3). Here, CXCL8 is linked to systemic lupus erythematosus.