ZFP36L1 (Zinc finger protein 36, C3H type-like 1) is one of several Zinc Finger Protein 36 family members, which could negatively regulate the post-transcriptional expression of targeted mRNAs through 3’ untranslated regions, including many inflammatory mediators and senescence-associated secretory phenotypes, suggesting ZFP36L1 was involved in the regulation of inflammation and senescence (Hyatt et al., 2014; Herranz et al., 2015; Wang et al., 2015), but the exact role of ZFP36L1 in AD pathogenesis remains unknown and requires further study to be fully clarified. Here, ZFP36L1 is linked to Alzheimer disease.