Among them, the expression levels of CDKN2A, SLC31A1, ATP7B, LIPT1, and MTF1 were higher, whereas FDX1, GLS, PDHA1, DLD, DLAT, PDHB, and LIAS gene expression levels were largely lower in AD cortex tissues than that in non-AD controls (Figures 2A–C). Here, LIAS is linked to Alzheimer disease.