At the same time, the obesity-related indicators (BMI, WG, HC, WHR, F%), obesity and menopause scale assessment (TCM clinical syndrome scores, modified Kupperman score, IWQOL-Lite, SF-36), and the changes in blood biochemical indicators (TC, TG, LDL-C, HDL-C, E2, FSH) will be assessed before and after therapy in this experiment as secondary outcomes. This evidence concerns the gene BRD2 and obesity due to melanocortin 4 receptor deficiency.