The positive expression of EGFR in gallbladder cancer tissues was 70.7% and 85.7% in gallbladder atypical hyperplasia tissues, while there was no positive expression in normal gallbladder tissues, speculating that there may be a close relationship between EGFR and the development of chronic cholecystitis and gallbladder cancer [24]. This evidence concerns the gene EGFR and Cholecystitis.