Based on our observations of a marked infiltration of inflammatory cells, including macrophages and leukocytes in inducible MSTs 41 and elevated proinflammatory cytokines in naïve Atg5flox/flox mice (Figure 1B), we first analyzed and compared leukocytes between tumor-bearing Atg5+/+ and Atg5flox/flox mice. This evidence concerns the gene ATG5 and neoplasm.