To test this possibility, we investigated host tumor microenvironment following the inoculation of KRASG12V;Atg5+/+ and KRASG12V;Atg5∆/∆ tumor cells, respectively, into different genotypic recipient mice (Atg5+/+ and Atg5flox/flox; Figure 1C). The gene discussed is ATG5; the disease is neoplasm.