LGR5 and infection: At Day 28 post injury, the Lgr5-mRNA level in the OE infected with Lenti-shLgr5-a was reduced by 48 ± 8% compared to infection with Lenti-shCtrl, while Lenti-shLgr5-b infection did not affect the Lgr5 expression level in the OE (Figure 5B).