Additionally, in the GSEA of GO (Figure S9E, 7E, S10E, S11E) and KEGG (Figure S9F, 7F, S10F, S11F) terms, T cell chemotaxis, T cell migration, response to IFN-γ, regulation of macrophage activation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt pathway, and NF-kappa B pathway, JAK-STAT pathway was more enriched in the high TIIClnc signature score group. The gene discussed is CD274; the disease is cancer.