Owing perhaps to the acute nature and severity of injury associated with myocardial infarction, several ncRNAs are downregulated in hypoxic-ischemic heart tissue in response to myocardial infarction, as previously shown for lncRNA HCP5, miR-21, miR-24, miR-30e, miR-98-5p, miR-150p, miR-185 and miR-212-5p 140-147, whereas other ncRNAs, such as lncRNA NEAT1 and miR-328-3p, are increased 148, 149. This evidence concerns the gene NEAT1 and myocardial infarction.