Remarkably, as early as 2 wk post-MI, CF-KO animals had a lower LV end-diastolic and end-systolic diameters (LVEDD and LVESD) when compared with the WT group, demonstrating an improvement in dilatative remodeling in the CF-KO mice (Figure 2B and 2C). Here, CFTR is linked to myocardial infarction.