With a galectin-3 cutoff value of 12.3 ng/ml (the highest quartile of galectin-3) for detecting the presence of myocardial fibrosis, a Qa >2 L/min increased the risk for myocardial fibrosis by 9.6-fold with this cutoff value (odds ratio = 2.97–31.23, p < 0.001). This evidence concerns the gene LGALS3 and Myocardial fibrosis.