SREBF1 and metabolic syndrome: Moreover, in an interesting study conducted on brown AT (BAT), physiologically involved in the control of energy homeostasis acting by dissipating energy to produce heat and inversely related to BMI, glucose level, and metabolic syndrome, Kariba et al. (56) found that BAT, induced by norepinephrine or cold exposure, beyond adipokines, can induce higher expression of miRNA-132, repressing hepatic Srebf1 expression, attenuating expression of lipogenic genes, and controlling the lipid metabolism in the liver.