CLEC7A and ischemic stroke: For instance, inhibiting Dectin-1 activity reduced infarct volume and improved functional outcomes 3 days after ischemic stroke (Ye et al., 2020), while stimulating Dectin-1 activity decreased axon density 3 days after spinal cord injury (Gensel et al., 2015) but promoted optic nerve regeneration 14 days after optic nerve crush injury (Baldwin et al., 2015).