* Levels of adiponectin and IL-1β are significantly modulated during the development of overweight and T2DM* Adiponectin levels are correlated with several pro‐inflammatory cytokines including IL-1β and with clinical parameters of obesity and T2DM.* Did not mention if age and sex were matched in the T2DM and the HC group. The gene discussed is IL1B; the disease is obesity due to melanocortin 4 receptor deficiency.