Our results showed that there was no significant difference in the expression of Tim-1 on CD4+ T cells between the two groups of T1D patients (7.56 ± 4.54 vs. 10.34 ± 5.37, P=0.063) (Figure 5A), whereas Tim-3 expression on CD4+ T cells from T1D in the remission phase was higher compared with T1D patients (6.43 ± 2.31 vs. 5.20 ± 1.82, P=0.043) (Figure 5B). Here, HAVCR2 is linked to type 1 diabetes mellitus.