HAVCR2 and type 1 diabetes mellitus: The results showed that the ratio of Tim-3 to Tim-1 expression in both the T1D (0.85 ± 0.89 vs. 2.13 ± 1.38, P<0.0001) and T2D patients (1.54 ± 1.48 vs. 2.13 ± 1.38, P=0.0387) was significantly lower than that in the HCs.