Therefore, although the recent changes in the immune-inflammatory network after CSM-TACE were complex, there was still overall consistency of changes, which further suggested that the simultaneous presence of acute inflammatory response and immune anti-tumor response may be a typical short-term postoperative CSM-TACE immunological phenomenon, the changes in IL-6 and Il-17A levels were more significant, but the changes in IFN-r and CD4+/CD8+T levels seem to be more specific. The gene discussed is IFNAR2; the disease is neoplasm.