IL-17A with double-sided characteristics showed a gradual decline process after CSM-TACE in patients with liver metastatic carcinoma, and it was negatively correlated with CD4+/CD8+T, the main reason was that with the significant necrosis of liver tumors, the tumor activity gradually decreased, and the body’s anti-tumor ability increased, then the IL-17A level decreased. This evidence concerns the gene IL17A and neoplasm.