HJURP was identified as an independent prognostic biomarker in iCCA (P = 0.041, HR = 5.23, 95% CI = 1.24–22.65) and pCCA (P = 0.009, HR = 3.25, 95% CI = 1.33–7.91). Here, HJURP is linked to infantile convulsions and choreoathetosis.