The analysis results revealed that the appropriate cut-off values for CA19-9, CEA, TB and CA19-9/TB, were 219.4 (p = 0.008), 5.8 (p = 0.138), 200 (p = 1.000) and 18.8 (p = 0.035), respectively. The gene discussed is CEACAM5; the disease is tuberculosis.