MPZL3 and cancer: Notably, the majority of MPZL3 expression positively correlated with DNAss and RNAss in the 33 TCGA cancers, which suggested that high MPZL3 expression predicted a high index of the tumor stemness score (DNAss and RNAss), strong activity of tumor stem cells and a low degree of tumor differentiation (Figures 6A, B).