We found that low expression of nine potential prognostic genes was significantly related to the poor prognosis of CRC patients (P<0.05), including ABCD3, ABHD6, GAB1, MIER1, MYOCD, PDE8A, RPS6KA5, TPM1 and WDR78 (Table 1). The gene discussed is RPS6KA5; the disease is colorectal carcinoma.