As shown in Figure 4B, ABCD3, ABHD6, GAB1, MIER1, MYOCD, PDE8A, RPS6KA5, TPM1 and WDR78 were altered in 4%, 6%, 5%, 6%, 10%, 6%, 6%, 5%, and 8% of the CRC samples respectively. The gene discussed is PDE8A; the disease is colorectal carcinoma.