Radiomics features from positron emission tomography (PET) imaging of 18F-fluorodeoxyglucose (FDG) markedly related to the activation and alteration of mTOR pathway genes in hepatocellular carcinoma (58), and similar results were also reported in BC that some immune-related pathways were associated with FDG-PET features, such as flux constants and static uptake (59), and some researchers also aimed to predict Ki-67 status from multiparametric MRI images (AUC: 0.79) in BC (60). The gene discussed is MKI67; the disease is breast cancer.