HOTTIP and cholangiocarcinoma: For instance, lncRNA SNHG3 promotes CCA cell proliferation and migration via mediating the miR-3173-5p/ERG axis (15); lncRNA FAM66C induces CCA growth, mobility, and glycolysis by modifying miR-23b-3p/KCND2 in vitro and in vivo (16); and lncRNA HOTTIP elevates drug resistance of gemcitabine and cisplatin via sponging miR-637 in CCA (18).