(55)found that pancreatic ductal adenocarcinoma (PDAC) cells incubated with TAMs or TAM cell-conditioned cultures (TAM-CM) showed higher migration and invasion rates than controls, and further demonstrated that TAMs induced EMT in PDAC cells via the TGF-β-Smad2/3/4-Snail signaling axis, leading to tumor cell migration. The gene discussed is TGFB1; the disease is neoplasm.