High RNF125 expression was associated with better RFS for tumor stage 1, grade 2 disease, female gender, white patients, Asian patients, sorafenib treatment, no alcohol intake, and hepatitis virus-free status, however, tumor stage 2, grade 1 disease, vascular infiltration, and female patients were not associated with OS (Tables 2, 3). The gene discussed is RNF125; the disease is neoplasm.