WNT4 secretion was evaluated in whole tissues of normal thymuses (six childhood and 10 aged NT) and thymic tumors (10 AB, 10B2 and 10B3 and 8TC) and was significantly higher in B3 thymomas and TCs compared with childhood and aged non-neoplastic thymuses (Figure 5A). This evidence concerns the gene WNT4 and thymoma.