The results showed that PDSS1 is significantly overexpressed in liver hepatocellular carcinoma (LIHC), bladder urothelial carcinoma (BLCA), esophageal carcinoma (ESCA), breast infiltrating carcinoma (BRCA), glioblastoma multiforme (GBM), uterine corpus endometrial carcinoma (UCEC), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC), pancreatic cancer (PAAD), and gastric cancer (STAD) (p<0.05;Figure 1A). The gene discussed is PDSS1; the disease is squamous cell lung carcinoma.