As shown in Fig. 5C, there were 11 microRNAs that could bind both SNHG16 and ABCB1, among which miR-214-3p (normal mean=26.69 reads per million mapped reads [RPM], tumor mean=7.29 RPM, P<0.001) was markedly reduced in CRC according to the TCGA data (Fig. 5D). The gene discussed is ABCB1; the disease is colorectal carcinoma.