Out of genes relevant to lung adenocarcinoma, any alterations in SMARCA4 were associated with shortened OS (HR 2.732, 95%CI 1.291-5.782, P=0.009) and DSS (HR 2.901, 95%CI 1.213-6.939, P=0.017) in univariable analysis. The gene discussed is SMARCA4; the disease is lung adenocarcinoma.