The previous studies reveal that some other genes are linked to FTD, including the VCP, CHCHD10, TBK1, CHMP2B, TARDBP, SQSTM1, FUS, UBQLN2, OPTN, TREM2, CYLD, PRKAR1B, TIA1, TUBA4A, CCNF, DCTN1, HNRNPA2B1, and HNRNPA1 [1, 2]. The gene discussed is OPTN; the disease is frontotemporal dementia.