In addition, the TRA CDR3 clonotypes ‘CATLDNYGQNFVF’ and ‘CAASRGSYIPTF’ (Fig. 4E), and the TRB CDR3 clonotype ‘CASSPAGANVLTF’ (Fig. 4F) were expanded in DDS-DIHS-4 patient and were also detected in blister cells of DDS-induced SJS. Here, THRB is linked to Schwartz-Jampel syndrome.