‘T’ allele of rs1143627 IL1B SNP was associated with higher level of depression (ZDS was 40.6±8.7, 39.2±7.3 and 38.3±8.0 in case of ‘T/T’, ‘T/C’ and ‘C/C’ genotypes, respectively, p-value=0.025 in log additive model). This evidence concerns the gene IL1B and depressive symptom measurement.