HM13 and hepatocellular carcinoma: Furthermore, difference analysis of TIICs infiltration levels between high- and low-HM13 expression subgroups was assessed by Wilcoxon signed-rank test based on the CIBERSORT algorithm and the result demonstrated that HCC patients with higher HM13 expression had modestly increased ratios of macrophages M0 and resting dendritic cells, while patients with lower HM13 expression had significantly elevated ratios of resting NK cell, macrophages.