NPPB and cardiovascular disorder: A series of biomarkers for cardiovascular disease have been identified, such as high-sensitivity C-reactive protein (hsCRP) [8], lipoprotein-associated phospholipase A2 (Lp-PLA2) [9], myeloperoxidase (MPO) [10], B-type natriuretic peptide (BNP), N-terminal prohormone BNP (NT-pro BNP) [11], leukocyte counts [12], as well as plasma metabolomics and circulating micro-RNAs [13, 14].