The blood proteins with the largest negative and positive effect sizes on HF were BAG3 (OR: 0.79, 95%CI: 0.74–0.85, PIVW = 2.59E-09) and MIF (OR: 1.19, 95%CI: 1.08–1.32, PIVW = 5.53E-04), respectively. The gene discussed is BAG3; the disease is hydrops fetalis.