CDON and hydrops fetalis: In weighted median MR, which is robust to invalid instruments [20] (variants with horizontal pleiotropy), 17 blood proteins (ABO, BAG3, CDON, APOA5, CCDC126, FLT4, IL15RA, ALDH3A1, PTHLH, RGMB, AMH, GLCE, TDGF1, FSTL1, FCGR2A, B3GAT3, MIF) remained significantly associated with HF (Suppl.