TNF and schizophrenia: A preclinical model of schizophrenia demonstrated elevated expression of Toll-like receptor (TLR)-3 signaling, interferon (IFN)-α and IFN-β in the frontal cortex (FC) of adult offspring subjected to MIA by polyinosinic:polycytidylic acid (poly(I:C)), during fetal life with increased oxidative and nitrosative stress, and increased levels of TNF-α, IFN-α, and IFN-β in the FC [63].