Tumours with low levels of FGFR4 showed the highest basal-like/squamous scores regardless of the FGFR1 status (either high or low); indeed, the signature scores between the FGFR4lowFGFR1high and FGFR4lowFGFR1low were not significantly different (Fig. 1D and Supplementary Fig. 1D). This evidence concerns the gene FGFR4 and neoplasm.