In an in vivo experiment, imipramine could also effectively attenuate tumor growth by suppressing the extracellular signal-regulated kinase (ERK)/NF-κB pathway activation.61 Gentian violet (GV) has an inhibitory effect on the survival and growth of cutaneous T-cell lymphoma (CTCL) tumors. Here, NFKB1 is linked to primary cutaneous T-cell non-Hodgkin lymphoma.