The necrotic apoptosis-related proteins (p-RIPK1, p-RIP3, and p-MLKL) in the cells treated with Su-X are significantly increased, suggesting that Su-X can inhibit the development of tumors by inducing necrotic apoptosis of tumor cells.306 Apoptosis inducers are largely related to cancer drug resistance. The gene discussed is MLKL; the disease is cancer.