Existing studies have shown that parthanatos is closely related to tumorigenesis and development.387 A study conducted microarray analysis on the expression of the PARP-1 gene in more than 8000 tumor samples.388 The results showed that the expression level of PARP-1 in breast cancer, ovarian cancer, endometrial cancer, lung cancer, skin cancer, and non-Hodgkin’s lymphoma was higher than that in the same amount of normal tissues, indicating that parthanatos was closely related to the above tumors. This evidence concerns the gene PARP1 and breast carcinoma.