NLRP3 and neoplasm: During the formation of the tumor and tumor microenvironment, pyroptosis has the dual effects of inhibiting and promoting its formation:335 on the one hand, inflammatory bodies released during pyroptosis can inhibit the proliferation and metastasis of tumor cells, and its mechanism is that NLRP3 inflammatory bodies produced by pyroptosis inhibit tumorigenesis by secreting inflammatory cytokines; On the other hand, the aggregation of inflammatory bodies contributes to the formation of tumor microenvironment and promotes tumor occurrence and development.