YAP is overexpressed in several types of malignant tumors and is involved in the occurrence and development of tumors, which may be a potential therapeutic target for cancer therapy.87 Verteporfin as a photosensitizer could inhibit the proliferation of pancreatic ductal adenocarcinoma (PDAC) PANC-1 and SW1990 cells, blocking cells at the G1 phase and further inducing apoptosis. The gene discussed is YAP1; the disease is cancer.