For example, blocking early autophagy by inhibiting ULK1 contributed to attenuating cell growth and overcoming the development of drug resistance in tumor therapy, while the activation of ULK1 could mediate the poor prognosis of tumors.210 At present, several small-molecule compounds that regulate the ULK1 have been extensively employed in cancer therapy (Table 7). Here, ULK1 is linked to neoplasm.