GSDMB and acute lymphoblastic leukemia: A study found two new gene association sites (17q12 and 8q24.21) related to the risk of childhood acute lymphoblastic leukemia.362 The peak slice size related to acute lymphoblastic leukemia in 17q12 is about 200KB, and the pyrolytic substrate GSDMB is also expressed in this fragment.362 At the gene level, GSDMB may affect the site expression of 17q12, thus affecting the risk of acute lymphoblastic leukemia; the relationship between GSDMB as a substrate causing cell death and the pathogenesis, treatment, and prognosis of acute lymphoblastic leukemia needs to be further studied.362