Terazosin was found to be neuroprotective in models of stroke, SMA and Parkinson's disease (PD).29, 30, 31 Indeed, patients with PD who had been prescribed terazosin, or other drugs with a similar PGK1-binding motif, had fewer hospital visits and a lower scores for both motor and non-motor symptoms.31 This evidence concerns the gene PGK1 and Parkinson disease.