ATM and neoplasm: This lack of differential uptake in the H1299 tumour xenografts mimics our in vitro uptake results in the same cells, indicating that the use of a radiolabelled ATMi for imaging ATM status may be challenging in a clinical setting, but still demonstrates the usefulness of [18F]1 to non-invasively measure whole body drug biodistribution and quantify tumour-drug uptake.