Finally, SCLCs and large cell neuroendocrine carcinoma (LCNEC) are neuroendocrine tumors (NETs) that usually have neuroendocrine differentiation properties and are defined by the specific expression of chromogranin A (CHGA), synaptophysin (SYP), and neural cell adhesion molecule 1 (NCAM1) [7]. The gene discussed is CHGA; the disease is neuroendocrine neoplasm.