Moreover, compared with the NC group, the DCM group of rats exhibited significantly higher levels of cardiac IFN-γ, IL-12Rβ2, IL-2, TNF-α, IL-17, and CCR5 mRNA transcripts, which were significantly mitigated or abrogated by treatment with single- or two-dose hUCMSCs (Fig. 3K). The gene discussed is TNF; the disease is familial dilated cardiomyopathy.