In serum of CT26 tumor-bearing mice, there was extensive overlap with the factors detected in CT26-conditioned media: following mediators identified in conditioned media showed at least a 1.2-fold increase in CT26 tumor-bearing mice: IL-1α, IL-2, IL-13, CCL2/5/19, LIX, CX3CL1, CXCL1/2/10 and CCL19 (Fig. 10b). The gene discussed is CX3CL1; the disease is neoplasm.