To understand obesity-related target genes, we used PubMed Abstracts, GeneCards, OMIM, and DisGeNET databases for network analysis, and identified 9481 common obesity-related genes, among which 1791 were screened out due to high relevance scores, such as Tbk1 and Ikbke. Here, TBK1 is linked to obesity due to melanocortin 4 receptor deficiency.