In this study, we identified five ferroptosis-related genes that are differentially expressed in BC, including ALB (albumin, Gene ID: 213), ANGPTL7 (angiopoietin like 7, Gene ID: 10218), BLOC1S5-TXNDC5 (BLOC1S5-TXNDC5 readthrough (NMD candidate), Gene ID: 100526836), IL6 (interleukin 6, Gene ID: 3569), and NGB (neuroglobin, Gene ID: 58157), and then developed a ferroptosis-related gene signature for BC patients. Here, TXNDC5 is linked to breast cancer.