Characterisation of Eμ-Myc/dCas9a-SAMKI/+/sgBcl-2 lymphomas revealed a B cell phenotype (CD19/B220 double positive; Fig. 4d and Supplementary Fig. 7a) and high BCL-2 expression (Fig. 4e), which are both also observed in human DHL21. The gene discussed is PTPRC; the disease is lymphoma.