HLA-C and COVID-19: These positions were changed to Tyr9, Ser11, Ala24, Ser77, Asn80, Ala90, Thr94, and Leu95, as are in HLA-C*08:02 allele, which belongs to group C1 and its frequency was significantly higher in individuals with mild COVID-19 (Fig 1A, left image), as well as to Asp9, Ala11, Ser24, Asn77, Lys80, Asp90, Ile94, and Ile95, as are in HLA-C*07:01 allele, which belongs to group C2 and its frequency was significantly higher in individuals with severe COVID-19 (Fig 1A, right graph).