Based on the availability and quality of PBMCs, we measured the expression of the SOCS3 protein by immunoblot in N = 5 CTRLs vs. N = 5 IPAH and N = 7 Associated-PAH patients (Fig. 6A and Supplementary Fig. 9). The gene discussed is SOCS3; the disease is idiopathic pulmonary arterial hypertension.